Simon & Schuster · Health & Longevity
The Switch
Ignite Your Metabolism with Intermittent Fasting, Protein Cycling, and Keto
How can you lose dramatic weight, reverse chronic conditions, and stay healthier longer? Flip the switch on your metabolism — backed by two decades of longevity research and over 1,100 scientific papers.
by James W. Clement
The Abstract
About the Book
Key Takeaways
- Activate autophagy — your body's built-in cellular self-cleaning mechanism
- Master intermittent fasting with practical, step-by-step protocols
- Understand the mTOR pathway and how it controls aging
- Implement protein cycling to optimize cellular repair
- Use ketogenic eating strategically to boost fat burning
- Reduce chronic inflammation and lower disease risk
- Slow the aging process with science-backed interventions
Within each of us is an ancient mechanism that eliminates toxic materials, initiates fat burning, and protects cells from becoming dysfunctional—or turning cancerous. It’s called autophagy, and when it’s turned on, the complex operation not only can slow down the aging process, it can optimize biological function as a whole, helping to stave off all manner of diseases and affording us the healthy life spans we never thought possible.
So how can we positively activate this switch? How frequently should we fast and for how long? Which foods dial up autophagy or, conversely, turn it down? How much exercise and what types are recommended? What’s the sweet spot between intermittent fasting, protein cycling, and ketogenic eating?
Backed by a wealth of scientific data and featuring a gallery of guidelines to follow for lasting results, The Switch decodes the science of autophagy and teaches you how to control it and maximize its profound impact.
James Clement spent years reading through more than 1,100 scientific papers before a groundbreaking realization: virtually all health-extending and lifespan-extending interventions work because of their actions on a single biological switch—mTOR. This book distills that research into a practical, accessible guide for anyone ready to take control of their metabolic health.
The Peer Review
What Experts Say
I was blown away by this book. Through many years of research and an immersion in cutting-edge research, James Clement has produced the best book I’ve read on fasting and autophagy. Definitely worth the read!”

David A. Sinclair, PhD
New York Times bestselling author of Lifespan
The Switch will undoubtedly rewrite your health destiny.

David Perlmutter, MD
New York Times bestselling author of Grain Brain and Brain Wash
James Clement is a rare trailblazer in scientific circles. The Switch offers a paradigm shift in the way we think about health—and how to avoid decline and illness. This is a must read.

Mark Hyman
#1 New York Times bestselling author of Food: What the Heck Should I Cook?
There is an easy way to make your cells stronger and younger. James Clement has done the science to crack the code for all of us to stay younger longer. Read this book!

Dave Asprey
Founder of Bulletproof and New York Times bestselling author of The Bulletproof Diet
The Switch is a sweeping and fascinating journey on the science of aging and life-extension. Additionally, Clement offers years of distilled research with a practical guide to switch on the body’s innate ability to rejuvenate itself to live a longer and healthier life.

Travis Christofferson
Author of Tripping Over the Truth and Curable
A must-read for anybody interested in promoting lifespan and health span.

Dr. Steve Horvath
Professor of Human Genetics & Biostatistics at UCLA
The Switch is a breakthrough twenty-first-century antiaging book!

Durk Pearson
Scientist and Coauthor of the #1 national bestseller Life Extension
Global Reach
Available Languages
English
The Switch
German
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Italian
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Turkish
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Hungarian
The Switch